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Report | Regular issue | Vol 14, No. 1, 1980, pp.55-58
Published online, 1st January, 1970
DOI: 10.3987/R-1980-01-0055
Use of N,N-Dimethyl(methylene)ammonium Chloride in the Functionalization of Indoles

Alan P. Kozikowski* and Hitoshi Ishida

*Department of Chemistry, University of Pittsburgh, Parkman Avenue & University Drive, Pittsburgh, PA 15260 , U.S.A.


The use of a preformed iminium salt has been found to provide superior yields in the generation of Mannich products from indoles.