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Communication | Regular issue | Vol 14, No. 1, 1980, pp.23-28
Published online, 1st January, 1970
DOI: 10.3987/R-1980-01-0023
The Total Synthesis of Diacetyloxodenudatine

Sat Paul Sethi, Roman Sterzycki, Wing Wah Sy, Rinaldo Marini-Bettolo, Thomas Y. R. Tsai, and Karel Wiesner*

*Natural Products Research Center, Department of Chemistry, University of New Brunswick, Bag Service #45222, Fredericton, New Brunswick, E3b 5A3, Canada


The total synthesis of racemic diacetyloxodenudatine (2) is described. Treatment of this material with LiAlH4 in dioxane at reflux caused the reduction of not only the lactam but also the exocyclic double bond and yielded racemic dihydrodenudatine (23).