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Report | Regular issue | Vol 12, No. 11, 1979, pp.1483-1485
Published online, 1st January, 1970
DOI: 10.3987/R-1979-11-1483
Synthesis of Heterocycles via Lactones. Part XI. A New Route to Yohimbane Skeleton-Synthesis of 17,18-Dimethoxy-15,16,17,18,19,20-hexadehydroyohimbane

Ganesh D. Pandey* and Kamla P. Tiwari

*Department of Chemistry, University of Allahabad, Allahabad, 211002, India

Abstract

A new synthesis of the yohimbane skeleton has been described. Condensation of the bromo ester (I) with tryptamine (II) gave the lactam (III) which was cyclized and reduced to get the title compound (V).