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Communication | Regular issue | Vol 12, No. 11, 1979, pp.1449-1451
Published online, 1st January, 1970
DOI: 10.3987/R-1979-11-1449
N-Alkylation of Lactams with Phase Transfer Catalyst

Hiroki Takahata,* Torahiko Hashizume, and Takao Yamazaki

*Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan

Abstract

N-Alkylation of lactams (1a,b,c) with alkyl halides (2) with phase transfer catalyst afforded various N-alkyl lactams (3,4, and 5) in good yields.