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Communication | Regular issue | Vol 12, No. 9, 1979, pp.1189-1190
Published online, 1st January, 1970
DOI: 10.3987/R-1979-09-1189
Total Synthesis of (±)-8S*-Descysteaminylthienamycin Protected woth o-Nitrobenzyl Groups

Tetsuji Kametani,* Shyh-Pyng Huang, and Masataka Ihara

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


(±)-trans-4-(2’,2’-Dimethoxyethyl)-3-(1’S*-hydroxyethyl)-2-azetidinone (4), prepared from an isoxazoline derivative (3), was converted to (±)-8S*-descysteaminylthienamycin protected with o-nitrobenzyl groups (8) using an intramolecular Wittig reaction.