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Communication | Regular issue | Vol 12, No. 9, 1979, pp.1171-1174
Published online, 1st January, 1970
DOI: 10.3987/R-1979-09-1171
A Novel One-step Synthesis of 3-Substituted 5,6-Dihydrothiazolo[2,3-c]-1,2,4-triazoles and -6,7-Dihydro-5H-1,2,4-triazolo[3,4-b][1,3]thiazines

L. G. Payne, M. T. Wu,* and A. A. Patchett

*Department of Process Reseach, Merck Research Laboratories, Division of Merck & Co., Inc., P. O. Box 200,0, Rahway, New Jersey 07065, U.S.A.

Abstract

3-Substituted-5,6-dihydrothiazolo[2,3-c]-1,2,4-triazoles and -6,7-dihydro-5H-1,2,4-triazolo[3,4-b][1,3]-thiazines have been synthesized in one step by reaction of the acid hydrazides with haloalkyl isothiocyanates.