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Communication | Regular issue | Vol 12, No. 4, 1979, pp.503-504
Published online, 1st January, 1970
DOI: 10.3987/R-1979-04-0503
Synthesis of Pyrimido[4,5-d]pyrimidines

Yoshinori Tominaga, Hiroto Okuda, Yoshiro Mitsutomi, Yoshiro Matsuda, Goro Kobayashi,* and Kanro Sakemi

*Faculty of Pharmaceutical Sciences, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8521, Japan

Abstract

5-Aminopyrimido[4,5-d]pyrimidine-2,4 (1H,3H)-diones were synthesized by the reaction of 6-aminouracil with dimethyl cyanoimidodithiocarbonate in the presence of potassium carbonate in dimethylformamide in good yields.