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Communication | Regular issue | Vol 12, No. 3, 1979, pp.353-357
Published online, 1st January, 1970
DOI: 10.3987/R-1979-03-0353
Quinazolinocarboline Alkaloids Chemistry: Reactivity of Euxylophorines — Part 1

Bruno Danieli, Giordano Lesma, and Giovanni Palmisano*

*Istituto di Chimica Organica, Facoltà di Farmacia, Università degli Studi di Milano, Via Venezian 21, I-20133 Milano, Italy


The quinazolinocarboline alkaloids of type (1a) and (1b) showed a marked regioselectivity towards nucleophilic reagents, (1a) reacting at C13b-N14 bond while (1b) cleaving the C5-N6 bond. The catalytic hydrogenation was also reported.