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Communication | Regular issue | Vol 9, No. 5, 1978, pp.647-652
Published online, 1st January, 1970
DOI: 10.3987/R-1978-05-0647
The Biosynthesis of Vindoline Using Cell Free Extracts from Mature Catharanthus roseus Plants

Kenneth L. Stuart, James P. Kutney,* Toshio Honda, Norman G. Lewis, and Brian R. Worth

*Department of Chemisry, University of British Columbia, Vancouver 8, V5T 1W5, Canada


Cell free extracts from mature Catharanthus roseus plants can biosynthesise vindoline (7, R = Ac) utilising 14C-tryptamine, secologanin (6) and S-adenosyl-methionine (methyl-14C).