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Report | Regular issue | Vol 6, No. 11, 1977, pp.1895-1899
Published online, 1st January, 1970
DOI: 10.3987/R-1977-11-1895
The Partial Synthesis of Structural Analogs of Tubulosine

Françoise Sigaut-Titeux, Louisette Le Men-Oliver, and Jean Le Men*

*Facluté de Pharmacie, UPRES-A/CNRS 6013, Insitut des Biomoleculés, 51, rue Cognacq-Jay, F-51096 Reims Cedex, France

Abstract

The two couples of title derivatives 4, 5 and 6, 7 were obtained from the Pictet-Spengler condensation of homoveratrylarmine with dihydrocorynantheal 2 and corynantheidal 3, respectively. Their structure and absolute configuration were determined on the basis of their mass and NMR spectra, and of their CD curves.