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Communication | Regular issue | Vol 6, No. 11, 1977, pp.1861-1864
Published online, 1st January, 1970
DOI: 10.3987/R-1977-11-1861
A Convenient Photoosynthsis of Aziridino-pyrrolo[1,2-a]benz[f]indoloquinones as Model Mitomycins in a One-pot Reaction

Mitsuo Akiba* and Toyozo Takada

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


The aziridinopyrrolo[1,2-a]benz[f]indoloquinones (4b) were photosynthesized as model mitomycins from 2-chloro-3-ethoxycarbonylcyanomethyl-1,4-naphthoquinone (1b) and 6-(4-bromophenyl)-3,6-diazabicyclo[3.1.0]hexane in a one-pot reaction.