Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 6, No. 11, 1977, pp.1833-1839
Published online, 1st January, 1970
DOI: 10.3987/R-1977-11-1833
Cyclodextrin-Nitrophenol Systems Studied by Polarography

Tetsuo Osa,* Tomokazu Matsue, and Masamichi Fujihara

*Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, sendai 980-8578, Japan


The effects of added α- and β-cyclodextrins on the half-wave potentials and the diffusion coefficients of o-, m-, and p-nitrophenols were examined, and a new polarographic method for determining the dissociation constants of cyclodextrin-substrate complexes was proposed. The dissociation constants of p-nitrophenol-cyclodextrin complexes obtained by polarographic method are in good agreement with those determined by spectrophotometric method. This polarographic method is applicable to many electroactive compound-cyclodextrin complexes whose dissociation constants can hardly be determined by spectrophotometric method.