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■ Synthetic Approaches to Streptonigrin and Biological Activities on the Quinolinequinone Systems

Satoshi Hibino*

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

The present review covers literatures on synthetic approaches to streptonigrin, metabolite of streptomyces flocculus. A summary of biological activities on the quinolinequinone systems is also presented. The contents of this review are as follows:
1. Introduction
2. Synthetic approaches to the quinoline- quinone systems
3. Synthetic approaches to the pyridine ring systems
4. Biological activities
5. Conclusion