Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 6, No. 5, 1977, pp.525-528
Published online, 1st January, 1970
DOI: 10.3987/R-1977-05-0525
Studies on Pyrimidine Derivatives. IV. Synthesis of Hydroxymethylpyrimidines by Means of the Homolytic Hydroxymethylation

Takao Sakamoto, Kazuko Konno, Takayasu Ono, and Hiroshi Yamanaka*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


2-Hydroxymethyl- and 4-hydroxymethyl-pyrimidines were synthesized in yield ranging from 28 to 93% by the reactions of some simple pyrimidine derivatives with the hydroxymethyl radical generated from methanol and ammonium peroxydisulfate.