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Communication | Regular issue | Vol 6, No. 4, 1977, pp.431-434
Published online, 1st January, 1970
DOI: 10.3987/R-1977-04-0431
A Synthesis of Flavins by the Reaction of 6-(N-Alkylanilino)-5-nitrouracils with Diethyl Azodicarboxylate in the Presence of Base

Fumio Yoneda* and Yoshiharu Sakuma

*Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-hon-machi, Kumamoto 862-0973, Japan


The treatment of 6-(N-alkylanilino)-5-nitrouracils with diethyl azodicarboxylate (DAD) in the presence of bases gave the corresponding isoalloxazines (flavins).