Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 6, No. 3, 1977, pp.285-290
Published online, 1st January, 1970
DOI: 10.3987/R-1977-03-0285
A Stereoselective Synthesis of Oxygenated Catharanthine Derivatives. Possible Precurors for Bisindole Alkaloids

Yasushi Honma and Yoshio Ban*

*Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan


In order to synthesize the bisindole alkaloids (Ia,b) of vinblastine type, catharanthine (IIa) was converted to the lactones (IIIa,b,c) and the epoxy derivatives (IVa,b), which would be available as the precursors for the synthesis of the above natural alkaloids.