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Communication | Regular issue | Vol 4, No. 8, 1976, pp.1337-1340
Published online, 1st January, 1970
DOI: 10.3987/R-1976-08-1337
The Reaction of 6-Methyl-7-azido-5,8-quinolinediones with Cyclic Secondary Amines. A Convenient Synthesis of 6-Substituted Aminomethyl-7-amino-5,8-quinolinediones

Shigetaka Yoshina* and Hsien-Saw Kuo

*Faculty of Pharmacy, Meijo University, 150 Yagoto, Tempaku-ku, Nagoya, Aichi 468-8503, Japan


The 6-methyl-7-azido-5,8-quinolinediones (Ia,b) react with amines (pyrrolidine, piperidine and morphorine) in benzene solution to give 6-substituted aminomethyl-7-amino-5,8- quinolinediones(IIIa-e).