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Communication | Regular issue | Vol 4, No. 7, 1976, pp.1267-1273
Published online, 1st January, 1970
DOI: 10.3987/R-1976-07-1267
Studies on the Synthesis of Bisindole Alkaloids. IV. Novel Oxygenated Catharanthine Derivatives

James P. Kutney,* Gordon H. Bokelman, Masahiro Ichikawa, Edwin Jahngen, Alummoottil V. Joshua, Ping-huang Liao, and Brian R. Worth

*Department of Chemisry, University of British Columbia, Vancouver 8, V5T 1W5 , Canada

Abstract

Electrophilic attack of various reagents on the 3,4-double bond of catharanthine derivatives (e.g. II, R = O) furnished novel intermediates, potentially useful in syntheses of naturally occurring bisindole alkaloids.