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Report | Regular issue | Vol 4, No. 5, 1976, pp.1013-1019
Published online, 1st January, 1970
DOI: 10.3987/R-1976-05-1013
A Synthesis of Aporphine Derivatives

Shinzo Kano,* Youko Takahagi, Eiji Komiyama, Tsutomu Yokomatsu, and Shiroshi Shibuya

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


A variety of 1-hydroxyaporphines have been synthesized via 6a,7-dehydroaporphines, obtained by the reaction between a series of 1-halogenobenzyl-3,4-dihydro-2- methylisoquinolinium iodides and dimsylsodium.