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Review | Regular issue | Vol 3, No. 5, 1975, pp.413-438
Published online, 1st January, 1970
DOI: 10.3987/R-1975-05-0413
Synthesis of Some N-Heterocycles Using Acetoacetamide Derivatives

Tetsuzo Kato,* Nobuya Katagiri, and Mohsen Daneshtalab

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

Reaction of ethyl acetoacetate (1), ethyl β-aminocrotonate (2), acetoacetamide (3), and β-aminocrotonamide (4) with carboxylic acid derivatives, aldehydes, ketones, and diketene results in the formation of N-heterocycles. This article gives a detailed survey of the reactions of these compounds and related derivatives.