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Review | Regular issue | Vol 3, No. 4, 1975, pp.343-361
Published online, 1st January, 1970
DOI: 10.3987/R-1975-04-0343
The Formation of Alkaloids in Mammalian Tissues

Arnold Brossi*

*The Department of Chemistry Research, Hoffman-La Roghe Inc., Nutley, New Jersey 07110, U.S.A.


Condensation of the amino acids L-dopa and L-tryptophan with acetaldehyde, a major metabolite of ethanol, may take place in mammalian systems. The following review summarizes the present knowledge on this interesting subject and includes the synthesis of a variety of substances which might be formed during such interactions.