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Communication | Regular issue | Vol 3, No. 2, 1975, pp.167-170
Published online, 1st January, 1970
DOI: 10.3987/R-1975-02-0167
The Total Synthesis of (±)-Mappicine

Tetsuji Kametani,* Hiromitsu Takeda, Hideo Neoto, and Keiichiro Fukumoto

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


Reduction of 7-methoxycarbonyl-8-methylindolizino[l ,2-b]quinolin-9(11H)-one (3), prepared from 7-methoxycarbonylindolizino[1,2-b]quinolin-9(11H)-one (2), gave the correspondmg alcohol (5), which was converted into (±)-mappicine (7) through the aldehyde (6).