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Communication | Regular issue | Vol 2, No. 6, 1974, pp.649-652
Published online, 1st January, 1970
DOI: 10.3987/R-1974-06-0649
Diazapolycyclic Compounds. IX. Substituted Diazaquinone Adducts with Dimethylenecyclohexane, Dimethylenecyclohexene and nSubstituted Butadienes

Berta López, Manuel Lora-Tamayo,* Pilar Navarro, and José Luis Soto

*Biochemistry Department, Kuwait University, Safat 13060, P.O. Box 5969, Kuwait


Substituted tetracyclic diaza compounds with varying positions of the nitrogen bridge have been synthesized by Diels-Alder reaction of substituted phthalazindiones with 1,2-dimethylenecyclohexane or 1,2- dimethylene-Δ4-cyclohexene and of naphthalazindiones with substituted butadienes in order to obtain compounds referable to tetracyclines of known activity.