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Communication | Regular issue | Vol 2, No. 5, 1974, pp.611-614
Published online, 1st January, 1970
DOI: 10.3987/R-1974-05-0611
1,4-Dipolar Reaction of 2,3-Dimethylisoquinolinium-4-dithiocarboxylate with Dimethyl Acetylenedicarboxylate

Kazumichi Mizuyama, Yoshinori Tominaga, Yoshiro Matsuda, and Goro Kobayashi*

*Faculty of Pharmaceutical Sciences, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8521, Japan


Reaction of 2,3-dimethylisoquinolinium-4-dithiocarboxylate with dimethyl acetylene-dicarboxylate in dimethylformamide gave 1,4a,6,10b-tetrahydro-3,4,11,12-tetramethoxycarbonyl- 4a,5-dimethyl-l-thioxo-6,10b-ethenothiapyrano[4,3-c]isoquinoline which might be resulted in both cycloaddition reactions, simultanious 1,4-dipolar cycloaddition and Diels-Alder reaction.