Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 2, No. 4, 1974, pp.457-460
Published online, 1st January, 1970
DOI: 10.3987/R-1974-04-0457
A Novel Synthesis of Pyrimidines. II. Cyclization of N-Cyano-cyanoacetamidines

Tadamasa Hirayama,* Masahiro Kamada, and Masataka Mimura

*Central Research Laboratoeies, Daiichi Pharmaceutical Co., Ltd., 16-13, Kitakasai 1-chome, Edsogawa-ku, Tokyo 134, Japan

Abstract

Cyclization reaction of N-cyano-cyanoacetamidines (III) with hydrogen chloride and bromide has been found to give 4,6-diamino-2-halogenopyrimidines (IV), but with hydrogen iodide to give an unexpected 4-amino-6-iodopyrimidine (V).