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Review | Regular issue | Vol 2, No. 3, 1974, pp.349-390
Published online, 1st January, 1970
DOI: 10.3987/R-1974-03-0349
Syntheses of Benzodiazocines

Tetsuji Kametani,* Kazuo Kigasawa, Mineharu Hiiragi, and Kikuo Wakisaka

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


Introduction of an additional nitrogen atom into a benzazocine (6,7-benzomorphan) ring gives a benzodiazocine (azabenzomorphan). The syntheses of twelve types of benzodiazocines are reviewed and some of their analgesic properties are discussed.