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Communication | Regular issue | Vol 2, No. 1, 1974, pp.67-72
Published online, 1st January, 1970
DOI: 10.3987/R-1974-01-0067
Semisynthetic β-Lactam Antibiotics. VII. New Semisynthetic Cephalosporins Derived from α-Sulfhenylacetic Acid

Hiroaki Nomura,* Takeshi Fugono, Takenori Hitaka, Isao Minami, Toshiyuki Azuma, Shiro Morimoto, and Toru Masuda

*Central Research Division, Takeda Chemical Industries, Ltd., 17-85 Jusohonmachi 2-chome, Yodogawa-ku, Osaka 532-8686, Japan


The preparation of derivatives of α-sulfophenylacetic acid has been made from 7-aminocephalosporanic acid. New semisynthetic cephalosporins exhibit a peculiar inhibitory effect against Pseudomonas aeruginosa.