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Communication | Regular issue | Vol 2, No. 1, 1974, pp.15-19
Published online, 1st January, 1970
DOI: 10.3987/R-1974-01-0015
Synthesis of a Non-Saccharical Analog of Puromycin

Frans M. Kaspersen, Hans Bieräugel, and Upendra K. Pandit*

*Organic Chemistry Laboratory, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands

Abstract

The synthesis of (2S,4S)-N-(p-methoxyphenyl-L-alanyl)-2-hydroxymethyl-4-[N9-6- (dimethylamino)purinyl]pyrrolidine (1), a non-saccharidal analog of puromycin, is described.