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Communication | Regular issue | Vol 1, No. 1, 1973, pp.5-10
Published online, 1st January, 1970
DOI: 10.3987/R-1973-01-0005
Studies on Indole Alkaloid Biosynthesis. VIII. The Later Stages of the Biosynthesis of Apparicine

James P. Kutney,* John F. Beck, and George B. Fuller

*Department of Chemisry, University of British Columbia, Vancouver 8, V5T 1W5, Vancouver 8, V5T 1W5

Abstract

Biosynthetic experiments with Aspidosperma pyricollum plants employing radioactively labelled forms of 16, 17-dihydrosecodin-17-ol (2) and secodine (3) reveal that the latter is incorporated intact during the biosynthesis of apparicine (1). These results provide important information about the later stages of biosyntheses of this alkaloid.