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Paper | Special issue | Vol 52, No. 3, 2000, pp.1105-1123
Published online, 1st January, 1970
DOI: 10.3987/COM-99-S85
Stereoselective Total Synthesis of Cephalosporolide D

Isamu Shiina,* Hidehiko Fujisawa, Toshihiro Ishii, and Yoshio Fukuda

*Department of Applied Chemistry, Faculty of Science, Science University of Tokyo, Kagurazaka 1-3, Shinjuku-ku, Tokyo 162-8601, Japan


An efficient method for the synthesis of (-)-cephalosporolide D is established via successive enantioselective aldol and effective 8-membered ring lactone forming reactions.