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Communication | Special issue | Vol 52, No. 2, 2000, pp.537-540
Published online, 1st January, 1970
DOI: 10.3987/COM-99-S76
A New Approach to the Synthesis of Chiral Tetraazacoronands Derived from L-Alanine

Agnieszka Szczepanska, Piotr Salanski, and Janusz Jurczak*

*Department of Chemistry, University of Warsaw, Pasteura St.1, 02-093 Warsaw, Poland


Dimethyl α,ω-dicarboxylates react under high pressure or ambient conditions with chiral primary diamino ethers derived from L-alanine to give the chiral cyclic diamides or tetramides in satisfactory yields. The effective preparation of chiral amino components starting from L-alanine is also described.