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Communication | Special issue | Vol 52, No. 2, 2000, pp.553-556
Published online, 1st January, 1970
DOI: 10.3987/COM-99-S73
Concise Synthesis of (±)-Brevioxime

Yutaka Nishimura and Takeshi Kitahara*

*Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

Abstract

Brevioxime (1) is a juvenile hormone (JH) biosynthesis inhibitor isolated from Penicillium brevicoinpactuin. The synthesis of race mic brevioxime (1) was accomplished in a straightforward manner via the β-ketoamido aldehyde.