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Paper | Special issue | Vol 52, No. 2, 2000, pp.599-602
Published online, 1st January, 1970
DOI: 10.3987/COM-99-S40
Chitinase-catalyzed Synthesis of Oligosaccharides by Using a Sugar Oxazoline as Glycosyl Donor

Shin-ichiro Shoda,* Toshitsugu Kiyosada, Hiroyuki Mori, and Shiro Kobayashi*

*Department of Materials Chemistry, Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan

Abstract

The regio- and stereoselective addition reaction of various methyl glycosides having an N-acetylglucosamine unit to the oxazoline derivative of N-acetyllactosamine has been achieved by using a chitinase as catalyst, giving rise to the corresponding oligosaccharides.