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Paper | Special issue | Vol 52, No. 3, 2000, pp.1231-1239
Published online, 1st January, 1970
DOI: 10.3987/COM-99-S136
The Synthesis of Bicyclic Piperazine-2-carboxylic Acids from L-Proline

Stephen Hanessian* and Raman Sharma

*Department of Chemistry, Université de Montréal, Montréal, Que’bec H3C 3J7, Canada


The stereocontrolled synthesis of two diastereomeric bicyclic piperazine-2-carboxylic acids from L-proline is described.