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Note | Regular issue | Vol 53, No. 3, 2000, pp.723-728
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8803
Two Isocoumarins from the Cultured Lichen Mycobiont of Graphis Sp.

Takao Tanahashi,* Yukiko Takenaka, Naotaka Nagakura, Nobuo Hamada, and Hiromi Miyawaki

*Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan


From the cultures of spore-derived mycobionts of lichen Graphis sp., two isocoumarins, 8-methyldichlorodiaportin (1) and 6,8-dimethylcitreoisocoumarin (2), were isolated. Their structures were determined by spectroscopic and chemical methods. This is the first instance of isolation of isocoumarin metabolites from lichen mycobiont.