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Note | Regular issue | Vol 53, No. 3, 2000, pp.717-722
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8799
12-Acetoxypseudopterolide: A New Diterpene from Pseudopterogorgia elisabethae

Athar Ata and Russell G. Kerr*

*Department of Chemistry and Biochemistry, Center for Molecular Biology and Biotechnology, Florida Atlantic University, 777 Glades Road, Boca Raton, Florida 33431, U.S.A.

Abstract

Chemical studies on the non polar fraction of the methanolic extract of Pseudopterogorgia elisabethae Bayer collected from the Florida Keys has yielded 12-acetoxypseudopterolide (1), a new diterpene of the pseudopterane series. The structure was established through spectroscopic analysis. Compound (1) was shown to exhibit modest anti-cancer activity against a human prostate cancer cell line (LnCap).