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Communication | Regular issue | Vol 53, No. 3, 2000, pp.529-533
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8779
1,3-Dihydro-1,3-diacetyl-2H -benzimidazol-2-one: A New Versatile and Selective Acetylating Agent

In Hwa Chung, Ki Suk Cha, Jae Hong Seo, Joong Hyup Kim, Bong Young Chung, and Choong Sup Kim*

*Biochemicals Research Center, Korea Institute of Science and Technology, P.O. Box 131, Seoul 130-650, Korea


1,3-Dihydro-1,3-diacetyl-2H-benzimidazol-2-one (4, DABI) was proven to be a versatile and selective acetylating agent for amines. Selectivity and reactivity are not only superior than those of other known acetylating agents, but also products could be easily separated with excellent yield.