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Paper | Regular issue | Vol 51, No. 11, 1999, pp.2627-2638
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8653
Palladium(0)-catalyzed Coupling of 6-Bromo and 3-Iodo Derivatives of 7-Methyl-4-oxo-1,4-dihydro[1,8]naphthyridines

Christophe Plisson and Jacques Chenault*

*Institut de Chimie Organique et Analytique, UMR CNRS 6005, Université d'Orléans, BP 6759, Rue de Chartres, 45067 Orléans Cédex 2, France

Abstract

Substituted 4-oxo-1,4-dihydro[1,8]naphthyridines were obtained with various substituents (aryl, alkyl, carbonyl chains) by functionalization at positions 6 and 3 using a Suzuki, Heck or Stille reaction.