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Communication | Regular issue | Vol 51, No. 9, 1999, pp.2035-2039
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8652
Synthesis of 3-Alkyl-5,6-diphenylpyrimidine-2,4-diones from N-Carbamoylsulfilimines and Diphenylcyclopropenone

Masahiko Takahashi,* Yuhsuke Kadowaki, Yasuo Uno, and Yoshiharu Nakano

*Department of Materials Sciences, Faculty of Engineering, Ibaraki University, 4-12-1 Nakanarusawamachi, Hitachi, Ibaraki 316-8511, Japan


3-Alkyl-5,6-diphenylpyrimidine-2,4-diones (uracil derivatives) have been prepared in moderate to good yields from N-carbamoylsulfihimines and diphenylcyclopropenone in one step. The alkyl group was regioselectively introduced into to the N-3 position of the pyrimidine ring.