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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Note | Regular issue | Vol 51, No. 8, 1999, pp.1913-1919
Published online, 1st January, 1970■ Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Ethyl Nipecotate-derived New Chiral Ligand
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8565
■ Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Ethyl Nipecotate-derived New Chiral Ligand
So Ha Lee, Dai Sig Im, Chan Seong Cheong,* and Bong Young Chung
*Medicinal Chemistry Research center, Life Science Division, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul 131-650, Korea
Abstract
(R)-(-)-Diphenyl-(N-methylpiperidin-3-yl)methanol (3) derived from (±)-ethyl nipecotate catalyzed the enantioselective addition of diethyizinc to various aldehydes in good to moderate optical yield (40 % - 81 %).
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