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Paper | Regular issue | Vol 51, No. 9, 1999, pp.2041-2063
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8514
Synthetic Studies towards the Synthesis of Western and Eastern Chloropeptin I, II Subunits

Georges Roussi,* Eduardo González Zamora, Annie-Claude Carbonnelle, and René Beugelmans

*Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique, Avenue de la Terrasse, Bat. 27, 91198 Gif-sur-Yvette Cedex, France


The western subunit (16-membered ring) was synthesized by the intramolecular SNAr reaction while the first 16-membered ring compound was obtained as a model of the eastern subunit via an intramolecular Ni0 mediated coupling reaction.