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Communication | Special issue | Vol 49, No. 1, 1998, pp.49-52
Published online, 1st January, 1970
DOI: 10.3987/COM-98-S12
Isolation, Partial Synthesis and Stereochemical Study of 10-Hydroxystrictosamide, a Constituent of Nauclea orientalis in Thailand

Hiromitsu Takayama,* Osamu Ohmori, Masayo Sakai, Michiko Funahashi, Mariko Kitajima, Dammrong Santiarworn, Boonsom Liawruangrath, and Norio Aimi

*Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan


From the Rubiaceous plant, Nauclea orientalis, in Thailand, seven non-alkaloidal and two glycosidic indole compounds were isolated. 10-Hydroxystrictosamide (5) and its pentaacetyl derivative (11) were prepared to determine the C3 stereochemistry.