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Communication | Special issue | Vol 50, No. 1, 1999, pp.57-62
Published online, 1st January, 1970
DOI: 10.3987/COM-98-S(H)42
Synthesis of Bicyclic Derivatives of 5a-Carba-sugars: 6-Hydroxyl Group Conformationally Restricted 5a-Carba-D-mannopyranose Derivatives

Seiichiro Ogawa,* Masatsugu Ohno, and Takashi Ohhira

*Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Kohoku-ku Yokohama 223-8522, Japan


Some bicyclic derivatives of 5a-carba-α-and β-D-manno-pyranoses, whose 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action GlcNAcT-V.