Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Regular issue | Vol 51, No. 3, 1999, pp.627-630
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8425
A Convenient and Facile Synthesis of 3-Trifluoromethyl-1,2,5-oxadiazoles with the Use of Silica Gel as an Effective Catalyst

Yasuhiro Kamitori*

*Department of Chemical Science andd Engineerring, Faculty of Engineering, Kobe University, Kobe 657-8501, Japan

Abstract

Silica gel catalyzed intramolecular dehydration of 1,1,1-trifluoro-alkane-2,3-dione dioximes (2) afforded 3-trifluoromethyl-1,2,5-oxadiazoles (3) in satisfactory yields.