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Paper | Regular issue | Vol 48, No. 8, 1998, pp.1537-1554
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8174
■ Synthesis of 7-Methyl Derivatives of 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid (DDATHF), 5,10-Dideaza-5,6,7,8-tetrahydrohomofolic Acid (HDDATHF), and LY254155

Edward C. Taylor* and Yao Wang

*Department of Chemistry, Princeton University, Princeton, New Jersey 08544, U.S.A.

Abstract

7-Methyl derivatives of DDATHF, homoDDATHF and the thiophene analog of DDATHF (LY254155) were prepared as potential antitumor agents.