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Communication | Special issue | Vol 46, No. 1, 1997, pp.111-114
Published online, 1st January, 1970
DOI: 10.3987/COM-97-S39
Chemoenzymatic Formal Synthesis of (-)-Indolmycin

Toshikazu Bando and Kozo Shishido*

*Institute for Medicinal Resources, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan

Abstract

An enantioselective formal total synthesis of indolmycin (1) has been accomplished based on the lipase mediated asymmetric acetylation of the prochiral diol (5).