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Note | Regular issue | Vol 48, No. 3, 1998, pp.545-547
Published online, 1st January, 1970
DOI: 10.3987/COM-97-8063
Synthesis of the 3a-(3-Indolyl)-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indole Core of Leptosins D-F

David Crich,* Ewa Fredette, and William J. Flosi

*Department of Chemistry, University of Illinois at Chicago, 845 West Taylor St. , Chicago, IL 60607-7061, U.S.A.


The Fischer indole reaction of aldehyde and phenyl hydrazine in the presence of zinc chloride smoothly provides the core structure of the leptosins D-F in good to excellent yield.