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Note | Regular issue | Vol 45, No. 11, 1997, pp.2247-2252
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7923
A Neoclerodane Diterpenoid from Scutellaria guatemalensis (Labiatae)

Baldomero Esquivel,* Rosa María Domínguez, Miguel Angel Martínez, and Georgina Espinosa-Pérez

*Instituto de Química, Universidad Nacional Autónama de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510 Mexico, D.F., Mexico


A new neoclerodane diterpenoid, (13R)-6α,11β-diacetoxy-1β,12α-diisobutyryloxy-4α,18;18β,13-diepoxy-neo-clerodan-15,16-olide (Scuteguatemalin) has been isolated from the aerial parts of Scutellaria guatemalensis besides the known skullcapflavone II. The structure of the new diterpenoid was established by spectroscopic methods and confirmed by X-Ray analysis.