HETEROCYCLES
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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Note | Regular issue | Vol 45, No. 10, 1997, pp.2015-2021
Published online, 1st January, 1970■ The Preparation of 1-Nonsubstituted and 1-Methyl- (and Ethyl)-1,4-dihydro-4-oxo- 3-quinolinesulfonamides from 4-Chloro-3-quinolinesulfonamides
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7887
■ The Preparation of 1-Nonsubstituted and 1-Methyl- (and Ethyl)-1,4-dihydro-4-oxo- 3-quinolinesulfonamides from 4-Chloro-3-quinolinesulfonamides
Leszek Skrzypek and Andrzej Maslankiewicz*
*Department of Organic Chemistry, The Medical University of Silesia, Jagiellonska Str. 4, 41-200 Sosnowiec, Poland
Abstract
4-Chloro-3-quinolinesulfonamides (1) were hydrolysed to 1,4-dihydro-4-oxo-3-quinolinesulfonamides (2) with boiling 18% hydrochloric acid. N-Alkyl-1,4-dihydro-4-oxo-3-quinolinesulfonamides (3) were prepared by quaternization of compounds (1) with dialkyl (methyl or ethyl) sulfate followed by hydrolysis of the quinolinium salt (4) formed.
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