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Paper | Regular issue | Vol 45, No. 8, 1997, pp.1559-1566
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7854
Constituents of the Seeds of Garcinia kola : Two New Antioxidants, Garcinoic Acid and Garcinal

Kenji Terashima, Tomoyuki Shimamura, Miho Tanabayashi, Mohammad Aqil, John A. Akinniyi, and Masatake Niwa

*Faculty of Pharmacy, Meijo University, 150 Yagoto, Tempaku-ku, Nagoya, Aichi 468-8503, Japan


Two new chromanols, named garcinoic acid and garcinal, were isolated together with a known chromanol, δ-tocotrienol and three known biflavonoids, garcinianin, GB-1 and GB-2, from the seeds of Garcinia kola Heckel (Guttiferae) collected in Nigeria and their structures were characterized on the basis of the spectroscopic and chemical evidence. Garcinoic acid, garcinal and δ-tocotrienol showed about 1.5 times stronger antioxidation activity than that of dl-α-tocopherol.